Reaction #3028219
Related Literature (1)
openreactiondata ↗doi:10.6084/m9.figshare.5104873.v1; patent:US09040751B2
Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: The dimethylamine and water streams were initially combined and preheated to 130° C. The stream of o-chlorobenzyl chloride was then introduced by way of a mixing chamber. The temperature in the reaction tube was set to approximately 140° C. After running through the reaction zone, the mixture was cooled and depressurized. The workup analogous to example 1 afforded the (2-chlorobenzyl)dimethylamine target product with a yield and purity as in example 3. preheated to 130° C was set to approximately 140° C the mixture was cooled
Source ID: ord-1ce7e88ae1444bdba8d0e8770aacc4b8